Friday, May 31, 2013

The Pharmacologic and Clinical Effects of Medical Cannabis

Cannabis was used for medicinal purposes dating back to 2737 BC. Since then eighteen states and the District of Columbia have allowed the use of medical marijuana. Currently two states, Colorado and Washington, have legalized the use of recreational marijuana.

Different forms of medical marijuana have had positive effects on treating pain for neuropathic, chronic, postoperative, and that related to fibromyalgia, rheumatoid arthritis, multiple sclerosis, and cancer. Some side effects noted were dry mouth, sedation, dizziness, tachycardia, conjunctive irritation, and hypotension. Additionally, medical marijuana decreases muscle spasms in people with multiple sclerosis.  

Marijuana causes psychiatric implications. Some people experience anxiety, disorientation, paranoia, and psychosis. Regular adolescent users are more prone to getting schizophrenia. Cannabis use is associated with impairments in memory and cognition. Extreme marijuana users have trouble in the encoding, storage, and retrieval of memory. Cannabis is also associated with depression and suicide.

The problems associated with medical marijuana depend greatly on the persons underlying conditions and the way they use marijuana. Additionally, the lack of quality control makes it hard for physicians to prescribe a certain formula of the drug. Also, patients that use medical marijuana need to be monitored for fear of addiction.  However, to make sure this does not happen, patients need to go through training programs, which most health systems do not have.


Cannabis is the most used and abused illicit drug. Although it does greatly help people with medical conditions, medical evidence is still lacking and should be used with caution.

http://onlinelibrary.wiley.com.ezaccess.libraries.psu.edu/doi/10.1002/phar.1187/full

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