Fahad B. Iqbal
Throughout the years, there has been research on the negative
and positive effects of marijuana on the human body and the brain. Marijuana is
frequently beneficial to the treatment of AIDS, cancer, glaucoma, multiple
sclerosis, and chronic pain. However, researchers have been working to explain
how marijuana has harmful effects on the functions of central nervous system
and hinders the memory and movement of the user's brain. Marijuana impinges on
the central nervous system by attaching to brain's neurons and interfering with
normal communication between the neurons. These nerves respond by altering
their initial behavior. For example, if a nerve is supposed to assist one in
retrieving short-term memory, cannabinoids receptors make them do the opposite.
So if one has to remember what he did five minutes ago, after smoking a high
dose of marijuana, he/she has trouble (Costandi, 2012). Marijuana plant
contains 400 chemicals and 60 of them are cannabinoids, which are psychoactive
compounds that are produced inside the body after cannabis is metabolized or is
extorted from the cannabis plant. Cannabinoids is an active ingredient of
marijuana (Costandi, 2012). The most psychoactive cannabinoids chemical in
marijuana that has the biggest impact on the brain is tetrahydrocannibol, or
THC. THC is the main active ingredient in marijuana because it affects the
brain by binding to and activating specific receptors, known as cannabinoid
receptors. These receptors control memory, thought, concentration, time and
depth, and coordinated movement. THC also affects the production, release or
re-uptake (a regulating mechanism) of various neurotransmitters.
When one's memory is affected by high dose of marijuana,
short-term memory is the first to be triggered. Marijuana's damage to
short-term memory occurs because THC alters the way in which information is
processed by the hippocampus, a brain area responsible for memory formation.
When a user has a high dose of marijuana, new information does not register
into their brain and this may be lost from memory and they are not able to
retrieve new information for more than a few minutes (Costandi, 2012).
There is also a decrease in the activity of nerve cells.
Marijuana also impairs emotions. When smoking marijuana, the user may have
uncontrollable laughter one minute and paranoia the next. This instant change
in emotions has to do with the way that THC affects the brain's limbic system.
The limbic system is another region of the brain that governs one's behavior
and emotions. The chemicals in marijuana bring cognitive impairment and
troubles with learning for the user. Smoking marijuana causes some changes in
the brain that are like those caused but cocaine, heroin, and alcohol. Some
researchers believe that has changes may put a person more at risk of becoming
addicted to other drugs such a cocaine and heroin (Costandi, 2012).
To prevent such harm, one must be cautious of their actions.
Even though marijuana has its positives, sometimes the negatives can outweigh
them. People just have to be careful about marijuana and use it in moderation.
Costandi, Mo. (March
1, 2012). How marijuana make you forget. Retrieved
from http://www.nature.com/news/how-marijuana-makes-you-forget-1.10152
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