PCE occurs in about 1% to 18% of pregnancies. It has before been shown that PCE can have negative effects in behavior and cognitive development as well as low birth weight. The new study, however, also draws a connection between drug use in offspring. This study serves as a predictor in early onset drug abuse and dependence. According to the study, "[a]t 15 years, 40% of those offspring who were prenatally exposed to cocaine had initiated marijuana use and 46% had initiated alcohol use, compared to 16% and 31% of nonexposed offspring, respectively." The study was also able to prove that PCE dictated adolescent substance abuse more so than other factors such as substance abuse in families, lack of parental supervision, childhood maltreatment, and exposure to violence, suggesting a direct causal relationship with PCE and substance abuse in adolescence.
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