Tuesday, June 11, 2013

Natural Reward Devaluation by Cocaine


            The article I chose this week discusses the negative effects and the natural reward devaluation caused by cocaine addiction.  Although cocaine is not a physically addicting drug, it can create a very complex psychological disease.  Undoubtedly, regular use of cocaine can lead to serious cardiovascular issues as well as brain damage; however, studies have also found that natural rewards become severely devalued as cocaine abuse increases.  Once important aspects of life such as friends, family, recreational activities, and health become far less important to an addict.  Consequently, addicts must continue to resort to cocaine in order to experience any sort of pleasure.  The drug, in a sense, becomes a crutch to the user despite all of these destructive effects.  Further studies show that there are three key factors responsible to this devastating cycle: the drug itself, stress, and cocaine-associated cues.  Cocaine cues represent anything that an addict may associate with drug use and are capable of triggering intense cravings.  Researchers “…hypothesize that the cocaine-paired taste in our model serves as a predictive cue of cocaine’s impending availability and precipitates the expression of a conditioned aversive state in learned anticipation of the future opportunity to self-administer cocaine.”  In other words, drug cues will trick the body into thinking they are about to receive the drug and can cause the subject to experience negative affective states such as dysphoria, irritability, and anhedonia until the drug is consumed.  Clearly, cocaine is a dangerous drug that appears to only harm the body physically as well and psychologically over time.


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